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galectin 7 lgals7 na na 36  (Galectin Therapeutics)

 
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    Structured Review

    Galectin Therapeutics galectin 7 lgals7 na na 36
    Galectin 7 Lgals7 Na Na 36, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/galectin-7/pm42316386-420-0-0
    Average 86 stars, based on 1 article reviews
    galectin 7 lgals7 na na 36 - by Bioz Stars, 2026-09
    86/100 stars

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    Related Articles

    Expressing:

    Article Title: Melanoma Proteomics Unveiled: Harmonizing Diverse Data Sets for Biomarker Discovery and Clinical Insights via MEL-PLOT.
    Article Snippet: Among these, Haptoglobin (HP, HR = 4.67, p = 2.8e-06), Galectin-7 (LGALS7, HR = 3.83, p = 2.9e-05), and Ubiquilin-1 (UBQLN1, HR = 3.2, p = 4.8e-05) emerged as the most interesting proteins with a considerable impact among the examined proteins. (Figure 3).

    Article Title: Salivary proteome and microbiome in pregnancy and postpartum: An exploratory study on the relation with arterial hypertension.
    Article Snippet: Galectin-7 (LGALS7) was significantly reduced in the saliva of women with AH (fold-change=2.12; p = 0.0076).

    Article Title:
    Article Snippet: 50kDa 40kDa Fig 2A ANGPTL4 β-actin 50kDa 40kDa Fig 2B AGS ANGPTL4 β-actin 50kDa 40kDa Fig 2B MKN7 ANGPTL4 β-actin 50kDa 40kDa Fig 2B SNU5 β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A MKN7 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 100bp 200bp 300bp 100bp 200bp 300bp 100bp 200bp 300bp Fig 3A MKN7 replication#2 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A MKN7 replication#3 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A AGS 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A AGS replication#2 194bp 118bp 203bp 195bp 176bp 132bp Fig 3A AGS replication#3 β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 194bp 118bp 203bp 195bp 176bp 132bp 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa Fig 3B MKN7 replication#1 Fig 3B AGS replication#1 ANGPTL4 Galectin-7 SHH Smo Gli-1 ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3B MKN7 replication#2 Fig 3B AGS replication#2 β-actin β-actin 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa 40kDa 50kDa 51kDa 86kDa 118kDa 15kDa ANGPTL4 Galectin-7 SHH 51kDa Smo Gli-1 Fig 3B MKN7 replication#3 β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3B AGS replication#3 β-actin 50kDa 15kDa 86kDa 118kDa 40kDa 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa LGALS7 ANGPTL4 15kDa 50kDa Fig 3E

    Article Title: Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Center Analysis.
    Article Snippet: Galectin-7 was expressed in epidermal keratinocytes in lesional skin of AD and released by IL-4/IL-13 stimulation, resulting in increased serum galectin-7 levels in AD patients [15].

    Article Title: Sweet Aging: Glycocalyx and Galectins in CNS Aging and Neurodegenerative Disorders
    Article Snippet: The galectin family consists of 15 distinct members, which are classified into three main structural types as follows: the proto-type galectins, with two identical CRDs (galectin-1, -2, -5, -7, -10, -11, -13, -14, and -15); chimera-type galectins, with one CRD and another distinct domain (galectin-3); and the tandem repeat galectins, which possess two CRDs with different carbohydrate specifities (galectin-4, -6,-8,-9, and -12) [ ].


    Article Title: Research progress of galectins in glioma
    Article Snippet: Galectin-2 and Galectin-4 are mainly expressed in the gastrointestinal tract [ , ], Galectin-7 is preferentially expressed in the skin [ ], Galectin-12 is abundantly expressed in adipose tissue [ ].

    Article Title: Research progress of galectins in glioma.
    Article Snippet: Galectin-2 and Galectin-4 are mainly expressed in the gastrointestinal tract [18, 19], Galectin-7 is preferentially expressed in the skin [20], Galectin-12 is abundantly expressed in adipose tissue [21].

    Biomarker Discovery:

    Article Title: Melanoma Proteomics Unveiled: Harmonizing Diverse Data Sets for Biomarker Discovery and Clinical Insights via MEL-PLOT.
    Article Snippet: Among these, Haptoglobin (HP, HR = 4.67, p = 2.8e-06), Galectin-7 (LGALS7, HR = 3.83, p = 2.9e-05), and Ubiquilin-1 (UBQLN1, HR = 3.2, p = 4.8e-05) emerged as the most interesting proteins with a considerable impact among the examined proteins. (Figure 3).

    Article Title: Salivary proteome and microbiome in pregnancy and postpartum: An exploratory study on the relation with arterial hypertension.
    Article Snippet: Galectin-7 (LGALS7) was significantly reduced in the saliva of women with AH (fold-change=2.12; p = 0.0076).

    Article Title:
    Article Snippet: 50kDa 40kDa Fig 2A ANGPTL4 β-actin 50kDa 40kDa Fig 2B AGS ANGPTL4 β-actin 50kDa 40kDa Fig 2B MKN7 ANGPTL4 β-actin 50kDa 40kDa Fig 2B SNU5 β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A MKN7 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 100bp 200bp 300bp 100bp 200bp 300bp 100bp 200bp 300bp Fig 3A MKN7 replication#2 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A MKN7 replication#3 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A AGS 194bp 118bp 203bp 195bp 176bp 132bp β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3A AGS replication#2 194bp 118bp 203bp 195bp 176bp 132bp Fig 3A AGS replication#3 β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 194bp 118bp 203bp 195bp 176bp 132bp 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa Fig 3B MKN7 replication#1 Fig 3B AGS replication#1 ANGPTL4 Galectin-7 SHH Smo Gli-1 ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3B MKN7 replication#2 Fig 3B AGS replication#2 β-actin β-actin 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa 40kDa 50kDa 51kDa 86kDa 118kDa 15kDa ANGPTL4 Galectin-7 SHH 51kDa Smo Gli-1 Fig 3B MKN7 replication#3 β-actin ANGPTL4 Galectin-7 SHH Smo Gli-1 Fig 3B AGS replication#3 β-actin 50kDa 15kDa 86kDa 118kDa 40kDa 50kDa 15kDa 51kDa 86kDa 118kDa 40kDa LGALS7 ANGPTL4 15kDa 50kDa Fig 3E

    Article Title: Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Center Analysis.
    Article Snippet: Galectin-7 was expressed in epidermal keratinocytes in lesional skin of AD and released by IL-4/IL-13 stimulation, resulting in increased serum galectin-7 levels in AD patients [15].

    Article Title: Sweet Aging: Glycocalyx and Galectins in CNS Aging and Neurodegenerative Disorders
    Article Snippet: The galectin family consists of 15 distinct members, which are classified into three main structural types as follows: the proto-type galectins, with two identical CRDs (galectin-1, -2, -5, -7, -10, -11, -13, -14, and -15); chimera-type galectins, with one CRD and another distinct domain (galectin-3); and the tandem repeat galectins, which possess two CRDs with different carbohydrate specifities (galectin-4, -6,-8,-9, and -12) [ ].


    Article Title: Research progress of galectins in glioma
    Article Snippet: Galectin-2 and Galectin-4 are mainly expressed in the gastrointestinal tract [ , ], Galectin-7 is preferentially expressed in the skin [ ], Galectin-12 is abundantly expressed in adipose tissue [ ].

    Article Title: Research progress of galectins in glioma.
    Article Snippet: Galectin-2 and Galectin-4 are mainly expressed in the gastrointestinal tract [18, 19], Galectin-7 is preferentially expressed in the skin [20], Galectin-12 is abundantly expressed in adipose tissue [21].



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    LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and <t>selective</t> <t>Galectin-7</t> expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown
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    LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and <t>selective</t> <t>Galectin-7</t> expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown
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    Image Search Results


    LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown

    Journal: Discover Oncology

    Article Title: Spatial transcriptomics of urothelial carcinoma with basal/squamous differentiation identifies Galectin-7 as a specific marker of squamous lineage commitment

    doi: 10.1007/s12672-026-04927-z

    Figure Lengend Snippet: LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown

    Article Snippet: It is highly expressed in normal stratified epithelia, and strong Galectin-7 expression has also been observed in benign squamous epithelial lesions such as cholesteatoma [ , ].

    Techniques: Expressing, Immunohistochemistry, Western Blot, Immunofluorescence, Proliferation Assay, Knockdown

    Diagnostic and prognostic value of Galectin-7 in urothelial carcinoma. A Immunohistochemistry (IHC) for p63 and Galectin-7 in UC with Ba/Sq features ( n = 28) and UC without Ba/Sq ( n = 64). B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 100 μm. C Summary of key clinicopathological parameters associated with Galectin-7 (G7) expression. Detailed clinicopathological data are provided in Supplementary Table 1. Kaplan–Meier analysis of progression-free survival stratified by Galectin-7 expression

    Journal: Discover Oncology

    Article Title: Spatial transcriptomics of urothelial carcinoma with basal/squamous differentiation identifies Galectin-7 as a specific marker of squamous lineage commitment

    doi: 10.1007/s12672-026-04927-z

    Figure Lengend Snippet: Diagnostic and prognostic value of Galectin-7 in urothelial carcinoma. A Immunohistochemistry (IHC) for p63 and Galectin-7 in UC with Ba/Sq features ( n = 28) and UC without Ba/Sq ( n = 64). B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 100 μm. C Summary of key clinicopathological parameters associated with Galectin-7 (G7) expression. Detailed clinicopathological data are provided in Supplementary Table 1. Kaplan–Meier analysis of progression-free survival stratified by Galectin-7 expression

    Article Snippet: It is highly expressed in normal stratified epithelia, and strong Galectin-7 expression has also been observed in benign squamous epithelial lesions such as cholesteatoma [ , ].

    Techniques: Diagnostic Assay, Immunohistochemistry, Expressing

    LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown

    Journal: Discover Oncology

    Article Title: Spatial transcriptomics of urothelial carcinoma with basal/squamous differentiation identifies Galectin-7 as a specific marker of squamous lineage commitment

    doi: 10.1007/s12672-026-04927-z

    Figure Lengend Snippet: LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown

    Article Snippet: B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests.

    Techniques: Expressing, Immunohistochemistry, Western Blot, Immunofluorescence, Proliferation Assay, Knockdown

    Diagnostic and prognostic value of Galectin-7 in urothelial carcinoma. A Immunohistochemistry (IHC) for p63 and Galectin-7 in UC with Ba/Sq features ( n = 28) and UC without Ba/Sq ( n = 64). B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 100 μm. C Summary of key clinicopathological parameters associated with Galectin-7 (G7) expression. Detailed clinicopathological data are provided in Supplementary Table 1. Kaplan–Meier analysis of progression-free survival stratified by Galectin-7 expression

    Journal: Discover Oncology

    Article Title: Spatial transcriptomics of urothelial carcinoma with basal/squamous differentiation identifies Galectin-7 as a specific marker of squamous lineage commitment

    doi: 10.1007/s12672-026-04927-z

    Figure Lengend Snippet: Diagnostic and prognostic value of Galectin-7 in urothelial carcinoma. A Immunohistochemistry (IHC) for p63 and Galectin-7 in UC with Ba/Sq features ( n = 28) and UC without Ba/Sq ( n = 64). B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 100 μm. C Summary of key clinicopathological parameters associated with Galectin-7 (G7) expression. Detailed clinicopathological data are provided in Supplementary Table 1. Kaplan–Meier analysis of progression-free survival stratified by Galectin-7 expression

    Article Snippet: B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests.

    Techniques: Diagnostic Assay, Immunohistochemistry, Expressing